Low MWCO (5 kD @ 50%) hydrophilic fiber for trapping smaller molecules. Suggested for recombinant proteins between 25 kD and 100 kD. Appropriate for suspension cell lines including CHO, HeLa and 293. Can support up to 109 cells and produce 100 µg/mL or more of recombinant protein in 20 mL ECS.
High MWCO (20 kD @ 50%) hydrophilic fiber for trapping larger recombinant proteins (120 kD on up depending upon glycosylation) hybridoma culture and lymphocyte culture. 20 kD MWCO allows TGF beta and TNF alpha to diffuse away while retaining antibodies. Can support up to 109 cells and produce 1-20 mg of a recombinant protein or 5-100 mg of monoclonal antibody every two days.