Cat # C2025 – 0.1 µm pore size for the highest exchange rates but without protein retention. 80 cm² outer surface area. PVDF fiber allow for the attachment of matrix proteins, cytokines and antibodies. Ideal fiber for endothelial cell culture under shear and various types of primary cell culture.

Cat # C2025D – 20 kD MWCO polysulfone fiber with 450 cm² of surface area. Only one wrap of oxygenation tubing to reduce system dead volume.

Cat # C2025F – 5 kD MWCO polysulfone fiber with 450 cm² of surface area. Only one wrap of oxygenation tubing to reduce system dead volume.

Cat # C2008 – Low MWCO (5 kD @ 50%) hydrophilic fiber for trapping smaller molecules. Suggested for recombinant proteins between 25 kD and 100 kD. Appropriate for suspension cell lines including CHO, HeLa and 293. Can support up to 10⁹ cells and produce 100 µg/mL or more of recombinant protein in 20 mL ECS.

Cat # C2011 – High MWCO (20 kD @ 50%) hydrophilic fiber for trapping larger recombinant proteins (120 kD on up depending upon glycosylation) hybridoma culture and lymphocyte culture. 20 kD MWCO allows TGF beta and TNF alpha to diffuse away while retaining antibodies. Can support up to 10⁹ cells and produce 1-5 mg of a recombinant protein every day or 5-100 mg of monoclonal antibody every two days.

Cat # C5011 – The scale-up of antibody production has just been made easier. The C5011 cartridge can be managed in the same manner as the C2011 but with 2X greater productivity and twice the antibody concentration. The C5011 is the same cartridge as the C2011 but with more than twice the oxygenation capacity.

Cat # C7011 – Hydrophilic PVDF with a .03um pore size is intended for antibiotic Pk/Pd applications where the drug compound being tested may be extremely hydrophobic and require high concentrations of solvent to maintain solubility, or demonstrates high levels of non-specific binding to the polysulfone fibers. One wrap of oxygenation tubing (.65M) reduces system dead volume to reduce reagent use. .03um pore size provides 100% bacteria retention, even for pleomorphic organisms, while permitting rapid exchange of drug across the fibers. Fibers are impregnated with glycerol so no pre-wetting is required.

Cat # C2003 – Low MWCO (5 kD @ 50%) hydrophilic fiber for trapping smaller molecules. Suggested for recombinant proteins between 25 kD – 100 kD.

Cat # C2018 – High MWCO (20 kD @ 50%) hydrophilic fiber for trapping larger recombinant proteins (100 kD or larger). Can support up to 5×10¹⁰ cells and produce 5-20 mg of protein every day in a volume of 60 mL. Appropriate for adherent or suspension cell lines including CHO, HeLa, BHK and 293 cells